Company Filing History:
Years Active: 1985-2010
Title: Gregory Tice: Innovator in Sepsis Diagnosis
Introduction
Gregory Tice is a notable inventor based in Lutherville, MD (US), recognized for his contributions to the field of medical diagnostics. He holds a total of 9 patents, focusing primarily on the early detection of sepsis, a life-threatening condition that requires prompt medical intervention.
Latest Patents
One of Tice's significant patents is related to the diagnosis of sepsis or Systemic Inflammatory Response Syndrome (SIRS) using biomarker profiles. This innovative approach allows for early prediction or diagnosis of sepsis, enabling clinical intervention before the disease progresses to severe stages, which are often associated with high mortality rates. The method involves comparing an individual's biomarker expression profile to those obtained from control populations, including individuals who have developed sepsis. This comparison allows clinicians to diagnose sepsis from a single bodily fluid sample, eliminating the need for prolonged patient monitoring.
Another important patent involves mass spectrometry techniques for determining an individual's sepsis status. This method compares a biomarker profile derived from a biological sample to a reference profile, classifying the individual as belonging to or not belonging to a reference population. The technique utilizes a decision rule, such as a classification tree, to determine the sepsis status without requiring knowledge of the specific biomarkers involved.
Career Highlights
Gregory Tice is currently associated with Becton Dickinson and Company Limited, where he continues to advance his research in medical diagnostics. His work has significantly impacted the field, particularly in improving the accuracy and speed of sepsis diagnosis.
Collaborations
Tice has collaborated with notable colleagues, including Thomas M Gentle, Jr and Paul Ernest Goldenbaum, contributing to the development of innovative diagnostic techniques.
Conclusion
Gregory Tice's work in the field of sepsis diagnosis exemplifies the importance of innovation in medical technology. His patents not only enhance early detection but also improve patient outcomes, showcasing the vital role of inventors in healthcare advancements.