Location History:
- Northwood, GB (2002)
- London, GB (2002 - 2020)
Company Filing History:
37 out of 57 
4 out of 151 
1 out of 1 Years Active: 2002-2020
Title: Gregory Gregoriadis: A Pioneer in Glycoprotein Modification
Introduction
Gregory Gregoriadis is a renowned inventor based in London, GB, known for his remarkable contributions to the field of glycoprotein modification. With an impressive portfolio of 40 patents, Gregoriadis has significantly influenced the landscape of biochemistry and drug delivery systems through his innovative approaches.
Latest Patents
His latest patents showcase groundbreaking advancements in the conjugation of water-soluble polymers to glycoproteins, enhancing their functionality and therapeutic potential. One notable patent focuses on the glycopolysialylation of non-blood coagulation proteins. This process involves conjugating a water-soluble polymer, particularly polysialic acid (PSA) or its modified form (mPSA), to an oxidized carbohydrate moiety of a glycoprotein or drug delivery system. The method enables forming oxime or hydrazone linkages between the polymer and carbohydrate moiety, resulting in innovative conjugates that hold promise for various therapeutic applications.
Another recent patent presents methods for synthesizing sialic acid derivatives for protein derivatization and conjugation. This process involves transforming the reducing terminal unit of polysaccharides into an aldehyde group while allowing for subsequent reactions with substrates like amines or hydrazines, thus forming non-cross-linked polysialylated compounds. These derivatives can be used with therapeutically useful drugs, peptides, or proteins, further showcasing Gregoriadis's aptitude for translational research.
Career Highlights
Gregory Gregoriadis's career has been punctuated by his association with prominent companies in the biopharmaceutical sector. Notable organizations include Lipoxen Technologies and Baxalta GmbH, where he has leveraged his expertise to drive innovation in drug delivery and biotherapeutics.
Collaborations
Throughout his career, Gregoriadis has collaborated with esteemed professionals in the field, including Peter Laing and Sanjay Jain. These partnerships have fostered an environment for knowledge exchange and have enriched the research landscape, facilitating the development of cutting-edge biotechnological solutions.
Conclusion
In conclusion, Gregory Gregoriadis stands out as a significant figure in the innovation of glycoprotein modification. His contributions, marked by 40 patents focusing on polysialic acid and its applications in drug delivery, reflect a deep commitment to advancing healthcare solutions. With a solid career foundation and a network of accomplished collaborators, Gregoriadis continues to shape the future of biochemistry and medicinal applications.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.