Gregor Jordan

Title: Gregor Jordan: Innovator in Immunoassay Technologies

Introduction

Gregor Jordan is a notable inventor based in Groebenzell, Germany. He has made significant contributions to the field of immunoassays, holding a total of 8 patents. His work focuses on developing methods that enhance the accuracy and efficiency of binding affinity determinations and anti-drug antibody quantification.

Latest Patents

One of his latest patents is titled "Immunoassay-based determination of in-solution binding kinetics." This patent describes a method for determining the binding affinity of a binder and its ligand through an immunoassay. The process involves analyzing the fraction of free binder in a sample containing binder, ligand, and binder-ligand complexes at various binder:ligand ratios. If the fraction of free binder is not consistent across these ratios, the binder:ligand ratio is adjusted, and the sample is re-analyzed to calculate the binding affinity.

Another significant patent is the "Target interference suppressed anti-drug antibody assay." This immunoassay quantifies the amount of anti-drug antibody that can specifically bind to a drug antibody, which in turn binds to a therapeutic target. The method includes several steps, such as incubating serum or plasma samples at specific pH values, forming complexes with capture and tracer antibodies, and quantifying these complexes to determine the amount of anti-drug antibody present.

Career Highlights

Throughout his career, Gregor Jordan has worked with prominent companies in the pharmaceutical industry, including Hoffmann-La Roche Inc. and F. Hoffmann-La Roche AG. His experience in these organizations has allowed him to refine his skills and contribute to groundbreaking innovations in immunoassay technologies.

Collaborations

Gregor has collaborated with notable colleagues, including Roland Staack and Uwe Dahl. These partnerships have fostered a collaborative environment that encourages the exchange of ideas and advancements in their field.

Conclusion

Gregor Jordan is a distinguished inventor whose work in immunoassays has led to significant advancements in the determination of binding affinities and anti-drug antibody quantification. His contributions continue to impact the pharmaceutical industry positively.