The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 27, 2024
Filed:
Dec. 29, 2020
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Martin Schaefer, Penzberg, DE;
Sylvia Rottach, Penzberg, DE;
Gregor Jordan, Penzberg, DE;
Kay-Gunnar Stubenrauch, Penzberg, DE;
Roland Staack, Penzberg, DE;
Kevin Brady, Basel, CH;
Hoffmann-La Roche Inc., Little Falls, NJ (US);
Abstract
Herein is reported a method for determining the concentration of a therapeutic antibody in a tissue of an experimental animal to whom the therapeutic antibody had been administered, wherein the interference from residual blood in a tissue sample of the experimental animal, which is used for determining the concentration of the therapeutic antibody in said tissue, is reduced by applying an inert reference antibody that does not penetrate into said tissue, whereby the inert reference antibody is administered 2 to 10 minutes prior to obtaining the tissue and blood sample.