Acton, MA, United States of America

Graham K Farrington

USPTO Granted Patents = 5 

 

Average Co-Inventor Count = 4.0

ph-index = 2

Forward Citations = 17(Granted Patents)


Company Filing History:


Years Active: 2001-2017

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5 patents (USPTO):Explore Patents

Title: The Innovative Contributions of Graham K. Farrington

Introduction

Graham K. Farrington is a notable inventor based in Acton, MA, with a significant impact in the field of therapeutic innovations. He holds five patents that focus on enhancing the transport of therapeutic molecules across the blood-brain barrier and developing light-targeting molecules for cancer treatment.

Latest Patents

One of his latest patents is titled "Enhancement of transport of therapeutic molecules across the blood-brain barrier." This invention is based on the discovery that a dimeric version of a BBB-transmigrating antibody, specifically the TMEM30A (CDC-50A) binding antibody, significantly improves transport across the blood-brain barrier compared to its monovalent counterpart, FC5. The invention provides molecules that enhance the transport of pharmacologically active agents across the blood-brain barrier, methods for increasing this transport, and treatment methods for disorders with neurological components. Another significant patent is "Light targeting molecules and uses thereof," which discloses LIGHT-targeting molecules, including LIGHT fusion molecules and anti-HER2 antibody molecules. This patent also includes pharmaceutical compositions and methods for using these molecules to treat, prevent, and diagnose hyperproliferative diseases, including cancer and metastasis.

Career Highlights

Graham K. Farrington has worked with prominent companies in the biotechnology sector, including Biogen Idec and Biogen. His work has contributed to advancements in therapeutic strategies and drug delivery systems.

Collaborations

Throughout his career, Farrington has collaborated with notable professionals, including Alexey Alexandrovich Lugovskoy and Werner Meier, enhancing the scope and impact of his inventions.

Conclusion

Graham K. Farrington's innovative work in enhancing therapeutic transport mechanisms and developing targeted cancer treatments showcases his significant contributions to medical science. His patents reflect a commitment to improving patient outcomes through advanced therapeutic strategies.

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