Glen S Cho

Title: Glen S Cho: Innovator in Antibody Derivatives and Engineered Proteins

Introduction

Glen S Cho is a notable inventor based in Newton, MA, who has made significant contributions to the field of biotechnology. He holds three patents that showcase his innovative approach to developing advanced therapeutic solutions. His work primarily focuses on antibody derivatives and engineered proteins, which have the potential to revolutionize medical treatments.

Latest Patents

One of Glen S Cho's latest patents is titled "Antibody derivatives with conditionally enabled effector function." This invention involves antibody derivatives that possess diminished effector function in their initial state due to the presence of disabling moieties. These moieties prevent engagement with the immune system's effector molecules, providing a novel method for controlling immune responses.

Another significant patent is for "Engineered thioredoxin-like fold proteins." This invention features compositions based on engineered thioredoxin-like fold protein domains, which include artificially diversified protein domains. The invention also outlines methods for identifying and preparing enriched compositions of target binding, loop-diversified ETRXs, enhancing their affinity, stability, selectivity, or solubility. Additionally, it includes compositions of ETRXs substituted with various groups, including proteins, nucleic acids, and small molecules.

Career Highlights

Glen S Cho is associated with The General Hospital Corporation, where he applies his expertise in biotechnology to advance research and development. His innovative work has positioned him as a key figure in the field, contributing to the understanding and application of antibody derivatives and engineered proteins.

Collaborations

Glen has collaborated with notable colleagues, including Brian Seed and Jia Liu Wolfe. These partnerships have fostered a collaborative environment that enhances the research and development of groundbreaking biotechnological solutions.

Conclusion

Glen S Cho's contributions to the field of biotechnology through his patents and collaborations highlight his role as an influential inventor. His work in antibody derivatives and engineered proteins continues to pave the way for advancements in medical treatments.