The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 11, 2022
Filed:
Jul. 27, 2016
Applicant:
The General Hospital Corporation, Boston, MA (US);
Inventors:
Glen S. Cho, Newton, MA (US);
Brian Seed, Boston, MA (US);
Assignee:
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/46 (2006.01); C12N 15/13 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2887 (2013.01); C07K 16/2803 (2013.01); C07K 16/3061 (2013.01); C07K 16/32 (2013.01); C07K 16/46 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01); C07K 2317/71 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2318/20 (2013.01); C07K 2319/00 (2013.01); C07K 2319/30 (2013.01); C07K 2319/32 (2013.01); C07K 2319/50 (2013.01);
Abstract
Antibody derivatives that have diminished effector function in the initial state owing to the presence of one or more disabling moieties that substantially prevent engagement of the antibody regions responsible for interaction with humoral and cellular immune system effector molecules, and methods of use thereof.