This inventor holds 8 USPTO granted patents and 8 published patent applications, plus 1 CIPO patent and 5 EPO patents. Top assignees: National Institute of Health and Medical Research, Assistance Publique-Hopitaux De Paris, Universite Paris 13 - Paris Nord. Active years: 2015-2021.
Company Filing History:
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Years Active: 2015-2021
Title: Giuseppina Caligiuri: Innovator in Molecular Imaging and Therapeutics
Introduction
Giuseppina Caligiuri is a prominent inventor based in Paris, France. She has made significant contributions to the field of molecular imaging and therapeutic agents, holding a total of 8 patents. Her work focuses on innovative solutions for inflammatory conditions and thrombotic diseases.
Latest Patents
One of her latest patents involves the use of CD31 as a molecular target for imaging inflammation. This invention discloses CD31 for use as a molecular imaging target in the detection of inflammatory conditions. The administration of the radiolabeled peptide P8RI as a CD31 ligand in various rat models of inflammation demonstrated that CD31 is present on activated cells in sufficient quantities to allow for a detectable signal. The noise signal from CD31 present on activated circulating cells and other non-involved organs or cells was minimal. Additionally, her patent includes a labeled CD31 ligand for use as a molecular imaging agent, which aids in determining whether a subject suffers from or is at risk of inflammatory conditions or recurrence after anti-inflammatory treatment. Another significant invention provides peptides corresponding to fragments of CD31 that inhibit platelet and leukocyte activation, which can be used in treating thrombotic diseases.
Career Highlights
Giuseppina has worked with esteemed institutions such as the Institut National de la Santé et de la Recherche Médicale and Université Paris 13 - Paris Nord. Her research has been pivotal in advancing the understanding and treatment of inflammatory and thrombotic diseases.
Collaborations
Throughout her career, Giuseppina has collaborated with notable colleagues, including Antonino Nicoletti and Sylvie Bay. These partnerships have contributed to her innovative research and development efforts.
Conclusion
Giuseppina Caligiuri's work in molecular imaging and therapeutic agents showcases her dedication to advancing medical science. Her inventions have the potential to significantly impact the diagnosis and treatment of inflammatory and thrombotic diseases.