The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 10, 2015
Filed:
Jun. 30, 2009
Applicants:
Giuseppina Caligiuri, Paris, FR;
Antonino Nicoletti, Paris, FR;
Inventors:
Giuseppina Caligiuri, Paris, FR;
Antonino Nicoletti, Paris, FR;
Assignee:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/53 (2006.01); G01N 33/543 (2006.01); G01N 33/68 (2006.01);
U.S. Cl.
CPC ...
G01N 33/54313 (2013.01); G01N 33/6878 (2013.01); G01N 2333/70503 (2013.01); Y10S 435/968 (2013.01); Y10S 435/973 (2013.01);
Abstract
The present invention stems from the finding that the extracellular domain of CD31 proteins present on blood leukocytes is shed and released in the circulation as a soluble form of CD31. A method for detecting shed CD31 is further disclosed. The invention therefore relates to a method for detecting a shed ectodomain of a transmembrane protein such as CD31 and to the use of such a method as a diagnostic tool. The invention further provides methods for determining whether a candidate protein is part of a molecular complex.