The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 09, 2019
Filed:
Jul. 27, 2015
Applicants:
Giuseppina Caligiuri, Paris, FR;
Antonino Nicoletti, Paris, FR;
Inventors:
Giuseppina Caligiuri, Paris, FR;
Antonino Nicoletti, Paris, FR;
Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/03 (2006.01); C07K 4/00 (2006.01); C07K 7/00 (2006.01); C07K 14/705 (2006.01); G01N 33/50 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/70503 (2013.01); G01N 33/505 (2013.01); A61K 38/00 (2013.01); G01N 2333/70596 (2013.01); G01N 2500/10 (2013.01);
Abstract
The present invention stems from the finding that the extracellular domain of CD31 proteins present on blood leukocytes is shed and released in the circulation as a soluble form of CD31. The invention relates to peptides corresponding to fragments of CD31 that inhibit T-cell response, and to their use in the treatment of thrombotic disorders such as atherothrombosis and autoimmune disorders.