Location History:
- Rome, IT (2010 - 2018)
- Grottaferrata, IT (2016 - 2021)
Company Filing History:
20 out of 51 
2 out of 8 
2 out of 376 
Years Active: 2010-2021
Title: Giovanni Monteleone: Innovator in Intestinal Fibrosis Treatment
Introduction
Giovanni Monteleone, based in Grottaferrata, Italy, is an accomplished inventor with a remarkable portfolio of 23 patents. His innovative work primarily focuses on therapies addressing intestinal fibrosis, which is a significant concern in gastrointestinal health.
Latest Patents
Among his latest patents, Monteleone has developed methods for treating intestinal fibrosis using SMAD7 inhibition. This invention details techniques for treating, preventing, or managing intestinal fibrosis by inhibiting SMAD7. It also encompasses methods to monitor treatment effectiveness through the use of a SMAD7 antisense oligonucleotide. In addition, these methods facilitate the regulation of SMAD7 antisense oligonucleotide treatment based on analyses of levels of Transforming Growth Factor-β (TGF-β), α-Smooth Muscle Actin (a-SMA), and phosphorylated Mothers Against Decapentaplegic Homolog 3 (p-SMAD3) levels. Furthermore, his inventions include antisense oligonucleotidic sequences against SMAD7, which are suitably modified for use as therapeutic agents in the medical field, particularly in treating chronic inflammatory bowel diseases such as Crohn's disease and ulcerative colitis.
Career Highlights
Giovanni Monteleone has made significant contributions to the pharmaceutical landscape through his work, including positions at several prominent companies. He has worked with Nogra Pharma Limited and Giuliani International Limited, where he played integral roles in advancing therapeutic innovations.
Collaborations
Throughout his career, Monteleone has collaborated with prominent colleagues in the field. Notable collaborators include Salvatore Bellinvia and Francesca Viti, with whom he has shared ideas and expertise to further the development of groundbreaking medical therapies.
Conclusion
In summary, Giovanni Monteleone stands out as a notable inventor in the field of intestinal health with a strong focus on the potential of SMAD7 inhibition for treating intestinal fibrosis. His numerous patents and collaborations exemplify his commitment to advancing medical treatments and improving patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.