The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 25, 2018
Filed:
Apr. 18, 2013
Applicants:
Nogra Pharma Limited, Dublin 2, IE;
University of Miami, Miami, FL (US);
Inventors:
Giovanni Monteleone, Grottaferrata, IT;
Peter Buchwald, Miami, FL (US);
Luca Inverardi, Miami, FL (US);
Antonello Pileggi, Miami, FL (US);
Camillo Ricordi, Miami, FL (US);
Alice Tomei, Miami, FL (US);
Assignees:
University of Miami, Miami, FL (US);
Nogra Pharma Limited, Dublin 2, IE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/113 (2010.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
C12N 15/113 (2013.01); A61K 9/0019 (2013.01); C12N 2310/11 (2013.01); C12N 2310/3341 (2013.01); C12N 2320/30 (2013.01);
Abstract
Disclosed herein are methods for treating/and or preventing diabetes using a specific inhibitor of SMAD7 expression or function. Also disclosed are methods of promoting organ and/or cell, e.g., pancreatic islet cell, survival after transplantation using a specific inhibitor of SMAD7 expression or function.