Giovanni Bucolo

Title: Giovanni Bucolo: Innovator in Biological Fluid Analysis

Introduction

Giovanni Bucolo is a notable inventor based in Cupertino, CA, recognized for his contributions to the field of biological fluid analysis. He holds a total of 3 patents that focus on innovative methods for determining substances in biological fluids. His work has significant implications for medical diagnostics and biochemical research.

Latest Patents

Giovanni Bucolo's latest patents include a method for determining a substance in a biological fluid and a reagent that enhances the accuracy of such determinations. This method involves oxidizing a compound produced during the determination in the presence of a dehydrogenase enzyme, which allows for the simultaneous production of reduced beta-nicotinamide adenine dinucleotide. This process is crucial for accurately measuring substances like alpha-amylase, transaminases, and triglycerides in biological fluids. Another significant patent focuses on determining transaminases in biological fluids, where L-glutamate is produced from alpha-ketoglutarate by transamination. This method also addresses interference from endogenous substances, ensuring precise measurements.

Career Highlights

Giovanni Bucolo is currently employed at Coulter Electronics, Inc., where he continues to develop innovative solutions in the field of diagnostics. His expertise in biochemical analysis has positioned him as a key contributor to advancements in medical technology.

Collaborations

Giovanni has collaborated with notable colleagues such as Mathew M Madappally and Gerald E Jaffe, enhancing the impact of his work through shared expertise and innovation.

Conclusion

Giovanni Bucolo's contributions to the field of biological fluid analysis through his patents and work at Coulter Electronics, Inc. highlight his role as a significant innovator in medical diagnostics. His methods not only improve accuracy but also pave the way for future advancements in the field.