Giovanna Scapin is a prominent inventor based in Staten Island, NY (US), known for her significant contributions to the field of cancer treatment. With a total of three patents to her name, she has made remarkable strides in developing innovative solutions for combating cancer.

Latest Patents

One of her latest patents involves the creation of crystals of anti-human PD-1 monoclonal antibodies. This invention includes crystals of pembrolizumab and structurally similar anti-PD-1 monoclonal antibodies, along with methods for producing these crystals. The compositions comprising these antibody crystals are particularly useful in the treatment of cancers. The invention provides a method for producing pembrolizumab crystals, which are suitable for X-ray diffraction. The inventors utilized these crystals to solve the three-dimensional structure of pembrolizumab to a resolution of 2.3 Å. Another notable patent focuses on substituted piperidines that increase p53 activity and their uses. This invention provides a compound that acts as an inhibitor of the HDM2 protein, along with pharmaceutical compositions and methods for treating cancer.

Career Highlights

Giovanna Scapin is currently associated with Merck Sharp & Dohme Corporation, where she continues to work on groundbreaking research and development in the pharmaceutical industry. Her work has been instrumental in advancing cancer therapies and improving patient outcomes.

Collaborations

Throughout her career, Giovanna has collaborated with esteemed colleagues, including Stephane L Bogen and Yao Ma. These partnerships have fostered innovation and contributed to the success of her research endeavors.

Conclusion

Giovanna Scapin's contributions to cancer treatment through her innovative patents and collaborations highlight her as a leading figure in the field. Her work continues to inspire advancements in medical research and therapy.

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