The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2014
Filed:
Oct. 05, 2010
Stephane L. Bogen, Somerset, NJ (US);
Yao MA, Lexington, MA (US);
Yaolin Wang, Short Hills, NJ (US);
Brian Robert Lahue, Millbury, MA (US);
Latha G. Nair, Edison, NJ (US);
Manami Shizuka, Lexington, MA (US);
Matthew Ernst Voss, Nassau, NY (US);
Margarita Kirova-snover, Troy, NY (US);
Weidong Pan, Somerset, NJ (US);
Yuan Tian, Newton, MA (US);
Bheemashankar A. Kulkarni, Bangalore, IN;
Craig R. Gibeau, Natick, MA (US);
Yuan Liu, Belmont, MA (US);
Giovanna Scapin, Staten Island, NY (US);
Diane Rindgen, North Plainfield, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Timothy J. Guzi, Sudbury, MA (US);
Danny J. Hicklin, Montclair, NJ (US);
Amin Nomeir, Milford, NJ (US);
Gerald W. Shipps, Jr., Stoneham, MA (US);
Malcolm Maccoss, Brookline, MA (US);
Stephane L. Bogen, Somerset, NJ (US);
Yao Ma, Lexington, MA (US);
Yaolin Wang, Short Hills, NJ (US);
Brian Robert Lahue, Millbury, MA (US);
Latha G. Nair, Edison, NJ (US);
Manami Shizuka, Lexington, MA (US);
Matthew Ernst Voss, Nassau, NY (US);
Margarita Kirova-Snover, Troy, NY (US);
Weidong Pan, Somerset, NJ (US);
Yuan Tian, Newton, MA (US);
Bheemashankar A. Kulkarni, Bangalore, IN;
Craig R. Gibeau, Natick, MA (US);
Yuan Liu, Belmont, MA (US);
Giovanna Scapin, Staten Island, NY (US);
Diane Rindgen, North Plainfield, NJ (US);
Ronald J. Doll, Convent Station, NJ (US);
Timothy J. Guzi, Sudbury, MA (US);
Danny J. Hicklin, Montclair, NJ (US);
Amin Nomeir, Milford, NJ (US);
Gerald W. Shipps, Jr., Stoneham, MA (US);
Malcolm MacCoss, Brookline, MA (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
The present invention provides a compound of Formula 1 as described herein or a pharmaceutically acceptable salt, solvate or ester thereof. The compounds are useful as inhibitors of the HDM2 protein. Also disclosed are pharmaceutical compositions comprising the above compounds and methods of treating cancer using the same.