Location History:
- Berryville, VA (US) (1983 - 2004)
- Ada, MI (US) (2007 - 2013)
Company Filing History:
6 out of 1,215 
6 out of 26 
2 out of 289 
Years Active: 1983-2013
Title: **George F. Vande Woude: Innovator in Cancer Research and Osteoarthritis**
Introduction
George F. Vande Woude, an esteemed inventor located in Ada, MI, has made remarkable contributions to the fields of cancer research and osteoarthritis through his innovative inventions. With a remarkable portfolio consisting of 14 patents, he stands as a prominent figure among inventors dedicated to advancing medical science for the betterment of human health.
Latest Patents
Vande Woude’s latest inventions include groundbreaking research on the disruption of mitogen inducible gene 6 (Mig-6) in knockout mice. This research has revealed significant insights into the early onset of osteoarthritis, characterized by symptoms such as joint enlargement, cartilage degradation, and the formation of bony outgrowths. Due to the striking similarities between Mig-6 knockout mice and human osteoarthritis, these mice serve as valuable models for exploring disease mechanisms and testing potential therapies. Furthermore, the research highlights Mig-6 as a tumor suppressor gene, implicating it in frequently observed genetic alterations associated with lung cancer.
Another notable invention includes the development of a monoclonal antibody, named Met4, which is specific to the receptor tyrosine kinase Met in a range of human solid tumors. The evidence indicates that the expression of Met correlates with aggressive cancer phenotypes and poor prognoses. The Met4 antibody is useful for detecting Met in formalin-fixed tissues, offering promising applications in diagnosis, prognosis, and therapeutic evaluation for cancer treatment.
Career Highlights
Throughout his illustrious career, George F. Vande Woude has held influential positions and collaborated with prestigious institutions. He has notably worked with the United States of America as represented by the Department of Health and the Van Andel Research Institute. His work continues to inspire upcoming scientists and researchers who aspire to make substantial contributions to medical research.
Collaborations
Among his respected colleagues, Vande Woude has worked alongside Donna Faletto and Beatrice S. Knudsen, both of whom share a strong commitment to advancing research in their respective fields. Their collective expertise and collaborative efforts have led to significant advancements in understanding complex diseases.
Conclusion
George F. Vande Woude's innovative research and contributions through his patents signify a dedication to unveiling the complexities of cancer and osteoarthritis, potentially leading to the development of new therapies and solutions for these challenging conditions. His work remains invaluable in the continuous pursuit of medical breakthroughs, demonstrating the powerful impact of innovation in healthcare.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.