The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 03, 2009
Filed:
Jun. 20, 2005
Applicants:
Han-mo Koo, Kentwood, MI (US);
Eunmi (Kay) Koo, Legal Representative, Kentwood, MI (US);
George F. Vande Woude, Ada, MI (US);
Nicholas S. Duesbery, Grand Rapids, MI (US);
Inventors:
Han-Mo Koo, Kentwood, MI (US);
Eunmi (Kay) Koo, legal representative, Kentwood, MI (US);
George F. Vande Woude, Ada, MI (US);
Nicholas S. Duesbery, Grand Rapids, MI (US);
Assignee:
Van Andel Research Institute, Grand Rapids, MI (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Inhibitors of the MAPK pathway, including MEK-directed proteases and small molecule inhibitors, are cytotoxic to human melanoma cells in vitro and in vivo via apoptotic mechanisms. These compounds are used to kill melanoma cells and to treat subjects with melanoma, either alone or in combination with other therapeutic modalities.