Gavril W Pasternak

USPTO Granted Patents = 18

Average Co-Inventor Count = 2.0

ph-index = 5

Forward Citations = 328(Granted Patents)

Location History:

New York, NY (US) (1986 - 2022)
(2023)

Company Filing History:

10 out of 559

Memorial Sloan Kettering Cancer Center

patents

6 out of 512

Sloan-kettering Institute for Cancer Research

University of Health Sciences & Pharmacy in St. Louis

patent

5. 1 out of 1,628

University of Southern California

patents

6. 1 out of 1,270

The University of North Carolina at Chapel Hill

patents

7. 1 out of 2,925

University of Florida Research Foundation, Incorporated

patents

8. 1 out of 5,307

Leland Stanford Junior University

patents

9. 1 out of 832,718

Other

patents

where one patent can have more than one assignee

Years Active: 1986-2023

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18 patents (USPTO):Sort by Forward CitationsExplore Patents

1. 11613547 - G-protein biased opioid receptor agonist/analgesics with reduced arrestin recruitment (2023-03-28),

2. 11213518 - Ligands of the mu, kappa, and delta opioid receptors (2022-01-04),

3. 11046692 - Mitragynine analogs and uses thereof (2021-06-29),

4. 10150775 - 6-amido derivatives of 4,5A-epoxymorphinans for treatment of pain (2018-12-11),

5. 9725457 - 6-amido derivatives of 4, 5-a epoxymorphinans for the treatment of pain (2017-08-08),

6. 7820688 - Topical anesthetic/opioid formulations and uses thereof (2010-10-26),

7. 7700122 - Topical compositions comprising an opioid analgesic and an NMDA antagonist (2010-04-20),

8. 7585941 - Mu opioid receptor splice variant polypeptides, polynucleotides and methods of screening compositions (2009-09-08),

9. 7087714 - Mu-Opiod receptor splice variant polypeptides (2006-08-08),

10. 6825203 - Topical anesthetic/opioid formulations and uses thereof (2004-11-30),

11. 6790855 - Topical anesthetic/opioid formulations and uses thereof (2004-09-14),

12. 6660496 - Nucleic acid molecules encoding a KOR3 kappa opioid receptor and the methods of producing the encoded receptor (2003-12-09),

13. 6627734 - Identification and characterization of multiple splice variants of the Kappa3-related opioid receptor (KOR-3) gene (2003-09-30),

14. 6509028 - Methods and compositions for treating pain of the mucous membrane (2003-01-21),

15. 6500927 - Identification and characterization of multiple splice variants of the mu-opioid receptor gene (2002-12-31),

Title: Gavril W Pasternak: Innovator in Opioid Research

Introduction

Gavril W Pasternak is a prominent inventor known for his significant contributions to the field of opioid research. He holds a total of 18 patents, showcasing his innovative approach to developing new analgesics. His work focuses on creating compounds that provide pain relief while minimizing the side effects commonly associated with traditional opiates.

Latest Patents

Among his latest patents is the development of G-protein biased opioid receptor agonists and analgesics with reduced arrestin recruitment. These compounds are designed to alleviate pain effectively while offering an improved pharmaceutical profile compared to other opiate derivatives. Another notable patent involves ligands of the mu, kappa, and delta opioid receptors. This invention is based on molecular dynamics simulations and aims to identify new opioid receptor ligands that can be utilized as analgesics, anti-diarrheal agents, and overdose reversal agents.

Career Highlights

Gavril W Pasternak has had a distinguished career, working at renowned institutions such as Memorial Sloan Kettering Cancer Center and the Sloan Kettering Institute for Cancer Research. His research has significantly advanced the understanding of opioid receptors and their potential therapeutic applications.

Collaborations

Throughout his career, Pasternak has collaborated with esteemed colleagues, including Ying-Xian Pan and Yuri Kolesnikov. These partnerships have contributed to the success of his research and the development of innovative solutions in pain management.

Conclusion

Gavril W Pasternak's work in opioid research has led to groundbreaking advancements in pain relief therapies. His innovative patents and collaborations continue to shape the future of analgesic development.

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