The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2003
Filed:
Dec. 05, 1997
Gavril W. Pasternak, New York, NY (US);
Ying-Xian Pan, New York, NY (US);
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Abstract
The subject invention provides recombinant nucleic acid molecule which encodes a kappa opioid receptor, and the receptor encoded thereby. The subject invention further provides related anti-sense oligonucleotide molecules. The subject invention further provides a related host vector system, and method for using same. The subject invention further provides polyclonal and monoclonal antibodies capable of specifically binding to kappa opioid receptor, methods for obtaining same, and methods of using same to detect the presence of, and quantitatively determine the amount of, kappa opioid receptor in a sample, image and quantitatively determine the amount of cell membrane-bound kappa opioid receptor present in a subject, determine a subject's potential sensitivity to a kappa opioid receptor-specific agent, determine the affinity of an agent for kappa opioid receptor, and identify agonists and antagonists of kappa opioid receptor.