Location History:
- Boulder, CO (US) (2010)
- Winchester, MA (US) (2017)
Company Filing History:
2 out of 2,896 
1 out of 832,912 Years Active: 2010-2024
Title: Gary J Brenner: Innovator in Tumor Treatment
Introduction
Gary J Brenner is a notable inventor based in Winchester, MA (US). He has made significant contributions to the field of tumor treatment, holding a total of 3 patents. His work focuses on innovative methods and compositions that aim to improve therapeutic outcomes for patients with tumors.
Latest Patents
One of his latest patents is titled "Methods and compositions relating to the treatment of tumors." This patent describes methods and compositions for treating tumors, such as schwannoma, by increasing the expression of Apoptosis-associated Speck-like protein containing a CARD (ASC) and/or gasdermin D. The increased expression is achieved through a vector or construct that includes a nucleic acid encoding ASC and/or gasdermin D, operably linked to a Schwann-lineage cell-specific promoter. In some embodiments, the vector is a viral vector.
Another significant patent is "AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors." This patent outlines compositions and methods for treating, inhibiting, preventing, and reducing the severity of schwannoma, as well as any disease or physiological state in which schwannoma plays a role. The compositions include an rAAV vector that contains a caspase-1 gene or a variant thereof, along with a Schwann cell-specific promoter.
Career Highlights
Throughout his career, Gary J Brenner has worked with reputable organizations, including The General Hospital Corporation. His innovative approaches to tumor treatment have positioned him as a key figure in the field of medical research.
Collaborations
Gary has collaborated with notable individuals such as Giulia Fulci and Xandra O Breakefield, contributing to advancements in tumor treatment methodologies.
Conclusion
Gary J Brenner's work in the field of tumor treatment exemplifies the impact of innovative thinking in medical research. His patents reflect a commitment to improving therapeutic strategies for patients facing challenging health conditions.