G Brett Robb is a prominent inventor based in Somerville, MA (US), known for his significant contributions to the field of RNA technology. With a total of 10 patents to his name, Robb has made remarkable advancements that have implications in biotechnology and medicine.

Latest Patents

Among his latest patents is the "Enzymatic RNA capping method," which provides an efficient way to cap RNA in vitro. This method allows for high-temperature capping reactions using Vaccinia capping enzyme or its variants. Additionally, the patent includes capping reactions that utilize enzymes from large viruses of amoeba, such as Faustovirus, mimivirus, or moumouvirus. Another notable patent is for "FCE mRNA capping enzyme compositions, methods and kits." This disclosure relates to the development of RNA vaccines with appropriate cap structures, utilizing non-naturally occurring single-chain RNA capping enzymes. The patent outlines systems and methods that may include an FCE variant with specific amino acid sequence characteristics.

Career Highlights

G Brett Robb is currently employed at New England Biolabs, Inc., a leading company in the field of molecular biology. His work focuses on innovative methods and compositions that enhance RNA technology, particularly in vaccine development.

Collaborations

Robb collaborates with notable colleagues, including Siu-Hong Chan and Mehul Ganatra, who contribute to the advancement of his research and innovations.

Conclusion

G Brett Robb's work in RNA capping technologies showcases his dedication to innovation in biotechnology. His patents reflect a commitment to improving RNA applications, which could have a lasting impact on the field.

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