The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 05, 2022
Filed:
Jun. 12, 2018
Applicant:
New England Biolabs, Inc., Ipswich, MA (US);
Inventors:
Bijoyita Roy, Medford, MA (US);
G. B. Robb, Somerville, MA (US);
Assignee:
New England Biolabs, Inc., Ipswich, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 48/00 (2006.01); C12P 19/34 (2006.01); A61K 31/713 (2006.01); C12N 9/12 (2006.01); A61K 31/7105 (2006.01); C12N 15/113 (2010.01);
U.S. Cl.
CPC ...
A61K 48/0091 (2013.01); A61K 31/713 (2013.01); A61K 31/7105 (2013.01); C12N 9/12 (2013.01); C12N 9/1247 (2013.01); C12N 15/113 (2013.01); C12P 19/34 (2013.01); C12Y 207/07006 (2013.01); C12N 2310/122 (2013.01); C12N 2310/141 (2013.01); C12N 2310/17 (2013.01);
Abstract
Provided herein, among other things, is a method for producing an RNA product that has reduced immunogenicity. In some embodiments, the method involves transcribing a template DNA with a thermostable RNA polymerase at a temperature of greater than 44° C.