Location History:
- Yokohama, JP (2010 - 2014)
- Kanagawa, JP (2006 - 2019)
Company Filing History:
7 out of 1,357 
5 out of 2,350 Years Active: 2006-2019
Title: Fumiaki Watanabe: Innovator in Nitrile Hydratase Technologies
Introduction
Fumiaki Watanabe, based in Kanagawa, Japan, has made significant contributions to the field of biotechnology, with a focus on enzymes like nitrile hydratase. With a total of 12 patents to his name, Watanabe's work reflects both innovation and practical applications in various chemical processes.
Latest Patents
Watanabe's latest patent concerns an improved nitrile hydratase exhibiting enhanced catalytic activity. This invention includes the DNA coding for the improved enzyme, a recombinant vector incorporating that DNA, and a transformant containing the recombinant vector. Additionally, the patent outlines methods of producing nitrile hydratase from cultures of the transformant, along with a systematic process for generating amide compounds using either the culture or its processed byproducts. The enhanced nitrile hydratase features an amino acid sequence denoted as SEQ ID NO: 50 (GXXXXDXXR) found in its beta subunit, where the variable amino acid "X" can be selected from a specific group including cysteine, aspartic acid, glutamic acid, histidine, isoleucine, lysine, methionine, asparagine, proline, glutamine, serine, and threonine.
Career Highlights
Throughout his career, Watanabe has been associated with renowned companies such as Mitsubishi Rayon Company, Limited and Mitsubishi Chemical Corporation. His innovative contributions have been pivotal in advancing the knowledge and application of enzymatic processes in industry.
Collaborations
Watanabe has collaborated with notable coworkers such as Ai Hara and Takanori Ambo. These collaborations have likely played a vital role in fostering innovation and bringing new products to market.
Conclusion
Fumiaki Watanabe's impressive portfolio of patents and his work on nitrile hydratase underlines his status as a leading inventor in the biotechnological field. His innovations not only showcase a commitment to scientific advancement but also hold the potential for significant industrial applications.