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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 10093912 B1

PDFFull Text
Date of Patent:
Oct. 09, 2018

Filed:

May. 12, 2015

Nitrile hydratase

Applicant:

Mitsubishi Chemical Corporation, Tokyo, JP;

Inventors:

Aya Kitahara, Tokyo, JP;

Takanori Akiyama, Kanagawa, JP;

Miki Wakamatsu, Kanagawa, JP;

Fumiaki Watanabe, Kanagawa, JP;

Assignee:

Mitsubishi Chemical Corporation, Tokyo, JP;

Attorney:

Oblon, McClelland, Maier & Neustadt, L.L.P.

Primary Examiner:

Ganapathirama Raghu

Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 13/02 (2006.01); C12P 21/06 (2006.01); C12P 19/34 (2006.01); C12N 15/00 (2006.01); C12N 1/20 (2006.01); C12N 1/00 (2006.01); C07H 21/04 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/88 (2013.01); C12P 13/02 (2013.01); C12Y 402/01084 (2013.01);
Abstract

Provided is a novel improved nitrile hydratase with improved resistance to amide compounds under high temperatures. Specifically provided is a nitrile hydratase having at least one amino acid mutation selected from (a) to (d) below, in the amino acid sequence expressed in SEQ ID NO:50 (Xto Xrepresent independent arbitrarily-defined amino acid residuals). (a) Xis valine or glycine (b) Xis valine or threonine (c) Xis an amino acid selected from a group consisting of isoleucine, leucine, methionine and threonine, (d) Xis leucine.

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Kitahara, Aya. (2018). Nitrile hydratase (U.S. Patent No. 10093912). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/10093912

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