Frederick H Eggars

Title: Innovations of Frederick H Eggars in Genetic Testing

Introduction

Frederick H Eggars is a notable inventor based in Sahuarita, AZ (US). He has made significant contributions to the field of genetic testing, particularly through his innovative methods for PCR and HLA typing. With a total of 3 patents, Eggars has developed techniques that enhance the efficiency and accuracy of genetic analysis.

Latest Patents

One of Eggars' latest patents focuses on methods for PCR and HLA typing using unpurified samples. This invention provides methods for amplifying a gene or RNA of interest using a tandem PCR process. The primers in the first PCR are locus-specific, while the second PCR uses primers that are specific for a sub-sequence of the locus-specific primers, which are completely consumed during the second PCR amplification. For RNA amplification, the first PCR involves reverse transcription, resulting in cDNA that serves as a template for cRNA synthesis, endpoint PCR, or real-time PCR. Additionally, this tandem PCR method can accept raw, unpurified mouthwash, cheek swabs, and ORAGENE-stabilized saliva as sample inputs. The resulting amplicons can then be used for complex, microarray-based genetic testing. Furthermore, the patent includes a method for allelotyping a gene or set of genes by amplifying them using tandem PCR on DNA or RNA from the sample.

Career Highlights

Throughout his career, Eggars has worked with various companies, including Genomics USA, Inc. His work has significantly impacted the field of genomics and genetic testing, showcasing his expertise and innovative spirit.

Collaborations

Eggars has collaborated with notable individuals in his field, including Michael E Hogan and Georgina Lopez Padilla. These collaborations have likely contributed to the advancement of his research and inventions.

Conclusion

Frederick H Eggars is a distinguished inventor whose work in genetic testing has led to innovative methods that improve the accuracy and efficiency of genetic analysis. His contributions continue to influence the field and pave the way for future advancements.