Frederic Paques

Title: Frederic Paques: Innovator in Genome Engineering

Introduction

Frederic Paques, based in Bourg la Reine, France, is a notable inventor recognized for his significant contributions to the field of genome engineering. With six patents to his name, Paques has played a crucial role in advancing methodologies in genetic engineering that have broad implications in non-therapeutic applications.

Latest Patents

One of his latest patents involves a method for preparing I-CreI meganuclease variants that possess modified cleavage specificity. This innovation is pivotal for cleaving new DNA targets and executing genetic and genome engineering tasks. The patent also addresses the nucleic acids that encode these variants, the expression cassettes that contain them, and the vectors employing these cassettes. This technology is designed for plants or animals (excluding humans) that have been transformed by the stated vectors. Furthermore, another of his patents highlights the use of meganucleases for inducing homologous recombination ex vivo and in toto within vertebrate somatic tissues, expanding their application in genome engineering and gene therapy.

Career Highlights

Frederic Paques has a rich professional history, having worked with renowned companies such as Cellectis and Cellectis S.A. His career reflects a dedication to pushing the boundaries of genetic engineering and embracing new technological advancements.

Collaborations

Throughout his career, Paques has collaborated with esteemed colleagues, including Sylvain Arnould and Patrick Chames. These partnerships have been instrumental in driving forward his innovative projects and expanding the reach of his inventions.

Conclusion

Frederic Paques stands as a prominent figure in the domain of genetic engineering, with his inventions and patents paving the way for future advancements. His work continues to influence the field and inspires the next generation of innovators.