Franziska Grassinger

Title: Franziska Grassinger: Innovator in Biochemical Engineering

Introduction

Franziska Grassinger is a prominent inventor based in Basel, Switzerland. She has made significant contributions to the field of biochemical engineering, particularly in the area of norcoclaurine synthases and the biosynthesis of alkaloids. With a total of 3 patents, her work has the potential to impact various applications in biotechnology and pharmaceuticals.

Latest Patents

Franziska's latest patents include innovative advancements in norcoclaurine synthases with increased activity. This invention focuses on specific mutations that enhance the activity of the condensation process between 4-HPAA and dopamine, leading to the production of (S)-norcoclaurine and/or 3,4-DhPAA and dopamine to (S)-norlaudanosoline. The identified mutations correspond to specific positions in the synthase, which are crucial for increasing activity compared to the wild type. Additionally, she has developed methods for increasing the biosynthesis of benzylisoquinoline alkaloids and their precursors in recombinant host cells. This involves engineering microorganisms and plant cells to reduce the activity of certain enzymes, thereby enhancing alkaloid production.

Career Highlights

Franziska Grassinger is currently associated with River Stone Biotech LLC, where she continues to push the boundaries of biochemical research. Her innovative approaches and discoveries have positioned her as a key figure in her field.

Collaborations

Franziska has collaborated with notable colleagues such as Philipp Friedrich Berninger and Esben Halkjaer Hansen. Their combined expertise has contributed to the advancement of their research projects and innovations.

Conclusion

Franziska Grassinger's work exemplifies the intersection of innovation and practical application in biotechnology. Her contributions to the field of norcoclaurine synthases and alkaloid biosynthesis highlight her role as a leading inventor in the industry.