The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 13, 2021
Filed:
Aug. 09, 2017
Applicant:
River Stone Biotech Llc, Cambridge, MA (US);
Inventors:
Esben Halkjaer Hansen, Frederiksberg, DK;
Markus Schwab, Lorrach, DK;
Philipp Berninger, Basel, CH;
Fanny Delgrange, Hagenthal-le-Haut, FR;
Franziska Grassinger, Basel, CH;
Assignee:
RIVER STONE BIOTECH, LLC, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12P 17/12 (2006.01);
U.S. Cl.
CPC ...
C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12P 17/12 (2013.01); C12Y 101/01001 (2013.01); C12Y 101/01006 (2013.01); C12Y 101/0109 (2013.01); C12Y 101/01021 (2013.01); C12Y 101/01026 (2013.01); C12Y 101/01034 (2013.01); C12Y 101/01035 (2013.01); C12Y 101/01041 (2013.01); C12Y 101/01046 (2013.01); C12Y 101/01049 (2013.01); C12Y 101/01076 (2013.01); C12Y 101/05003 (2013.01);
Abstract
Recombinant microorganisms, plants, and plant cells are disclosed that have been engineered to have reduced levels or activity of one or more alcohol dehydrogenases or aldehyde reductases thereby increasing the production of benzylisoquinoline alkaloids and/or benzylisoquinoline alkaloid precursors.