Location History:
- Boston, NY (US) (2013)
- Boston, MA (US) (2004 - 2021)
Company Filing History:
9 out of 8,373 
6 out of 504 
2 out of 2 
Years Active: 2004-2021
Title: Frank B Gertler: Innovator in Cancer Research
Introduction
Frank B Gertler is a prominent inventor based in Boston, MA (US), known for his significant contributions to cancer research. He holds a total of 9 patents, showcasing his innovative approaches to understanding and treating cancer.
Latest Patents
Gertler's latest patents include groundbreaking methods involving Mena screening for inhibitors of cancer invasion and metastasis. These methods and compositions are designed for diagnosing or inhibiting the invasion or metastasis of cancer in a subject based on Mena. Another notable patent focuses on identifying and treating invasive or metastatic breast cancers. This research highlights the mesenchymal mode of cancer cell invasion, which is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. The compositions and methods described aim to assess and treat subjects with metastatic cancer or those at risk of developing it, particularly metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels.
Career Highlights
Throughout his career, Gertler has worked with esteemed institutions such as the Massachusetts Institute of Technology and Albert Einstein College of Medicine. His work has significantly advanced the understanding of cancer biology and therapeutic strategies.
Collaborations
Gertler has collaborated with notable colleagues, including John S Condeelis and Madeleine J Oudin, further enhancing the impact of his research in the field of cancer.
Conclusion
Frank B Gertler's innovative work in cancer research has led to important advancements in the diagnosis and treatment of metastatic cancers. His contributions continue to influence the scientific community and improve patient outcomes.