The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 27, 2018
Filed:
Feb. 24, 2012
Frank B. Gertler, Boston, MA (US);
Christopher Boyce Burge, Belmont, MA (US);
Irina M. Shapiro, Chestnut Hill, MA (US);
Wu Albert Cheng, Somerville, MA (US);
John S. Condeelis, Bronx, NY (US);
Maja H. Oktay, Rye, NY (US);
Frank B. Gertler, Boston, MA (US);
Christopher Boyce Burge, Belmont, MA (US);
Irina M. Shapiro, Chestnut Hill, MA (US);
Wu Albert Cheng, Somerville, MA (US);
John S. Condeelis, Bronx, NY (US);
Maja H. Oktay, Rye, NY (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Montefiore Medical Center, Bronx, NY (US);
Albert Einstein College of Medicine, Inc., Bronx, NY (US);
Abstract
The present invention provides a method for identifying a tumor as likely to metastasize, or likely to have metastasized, comprising obtaining a sample of the tumor and quantitating alternatively spliced mRNA isoforms of a cell motility gene, a cell adhesion gene and/or an actin cytoskeletal remodeling gene in the sample, or any specified genes or the level of RNA binding proteins compared to a predetermined non-metastasizing control.