The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 15, 2019
Filed:
Mar. 06, 2017
Massachusetts Institute of Technology, Cambridge, MA (US);
King's College London, London, GB;
Frank B. Gertler, Boston, MA (US);
Guillaume Carmona, Boston, MA (US);
Matthias Krause, London, GB;
Upamali Perera, London, GB;
MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, MA (US);
KING'S COLLEGE LONDON, London, England, GB;
Abstract
Cancer invasion is a hallmark of metastasis. The mesenchymal mode of cancer cell invasion is mediated by elongated membrane protrusions driven by the assembly of branched F-actin networks. Described herein are compositions and methods for assessing and treating a subject having metastatic cancer or at risk of developing metastatic cancer, e.g., metastatic breast cancer, through the determination of Lamellipodin protein or gene expression levels in the subject.