Company Filing History:
4 out of 49 
2 out of 60 
Years Active: 2018-2020
Title: The Innovative Mind of Francis Rodier
Introduction
Francis Rodier, based in Novato, California, is a prominent inventor with a remarkable portfolio of four patents. His contributions to the field of aging research have significant implications for understanding age-related disorders and advancing potential therapeutic approaches.
Latest Patents
Rodier's latest patents focus on innovative methods to target senescent cells, a critical aspect of aging and health deterioration. One of his notable inventions is the "Nucleic acid construct with a p16 promoter that causes a prodrug converting enzyme to be expressed specifically in senescent cells." This groundbreaking patent offers a non-human animal model for studying age-related disorders and allows researchers to identify therapeutic agents that can treat or prevent these conditions.
Additionally, Rodier developed a "Transgenic mouse having a transgene that converts a prodrug into a cytotoxic compound in senescent cells." This invention involves a transgene regulated by a p16 promoter that directs enzyme expression to senescent cells. As a result, administering the prodrug selectively targets and eliminates these cells, effectively delaying the progression of related disorders. The model also includes a 3MR mouse, which is equipped with bioluminescent and fluorescent markers to visualize senescent cells.
Career Highlights
Throughout his career, Francis Rodier has collaborated with esteemed institutions such as the Buck Institute for Research on Aging and Erasmus University Medical Center Rotterdam. His work significantly contributes to our understanding of the biology of aging and the development of potential interventions.
Collaborations
Rodier has worked closely with notable researchers, including Judith Campisi and Marco Demaria. These collaborations have fostered advancements in the study of cellular senescence and its effects on aging, showcasing the power of teamwork in scientific research.
Conclusion
Francis Rodier's innovative spirit and dedication to age-related research not only highlight his role as a leading inventor but also pave the way for future discoveries in combating age-related disorders. With his patents, he contributes valuable insights that may lead to transformative therapies, ultimately enhancing the quality of life as we age.