Location History:
- Oakland, CA (US) (1987 - 1997)
- Davis, CA (US) (1997 - 1998)
Company Filing History:
7 out of 212 
4 out of 4,948 
1 out of 622 
Years Active: 1987-1998
Title: Frances C. Lawyer: Innovator in Recombinant DNA Technology
Introduction
Frances C. Lawyer is a notable inventor based in Oakland, California, credited with 12 patents primarily focused on advancements in recombinant DNA technology. His innovative approaches have significantly contributed to the field of molecular biology, particularly in developing tools for DNA amplification and purification processes.
Latest Patents
Among Frances's most recent patents are two groundbreaking inventions:
1. **Recombinant Expression Vectors and Purification Methods for Thermus** - This patent describes recombinant DNA sequences encoding the DNA polymerase activity of *Thermus thermophilus*, which can be employed to create recombinant vectors and transformed host cells for producing the activity. The DNA polymerase from *T. thermophilus* is a protein weighing approximately 94 kDa, which is especially beneficial in the polymerase chain reaction (PCR) process.
2. **Purified Thermostable Nucleic Acid Polymerase Enzyme from Thermotoga** - This invention details a purified thermostable enzyme derived from the eubacterium *Thermotoga maritima*, with a molecular weight of about 97 kilodaltons and DNA polymerase I activity. The enzyme can be cultivated from native or recombinant host cells and utilized with primers and nucleoside triphosphates during a temperature-cycling chain reaction, where specific nucleic acid sequences are amplified.
Career Highlights
Frances C. Lawyer has held significant roles in renowned companies, including Cetus Corporation and Hoffmann-La Roche Inc., where he applied his expertise to foster innovation and advance molecular biology techniques. His contributions have helped pave the way for more efficient and effective tools used in genetic research and diagnostics.
Collaborations
During his career, Frances has worked alongside esteemed colleagues such as David H. Gelfand and Susanne Stoffel. Their collaborative efforts have further enriched the discoveries and advancements in DNA technology and polymerase applications, enhancing research capabilities in numerous laboratories.
Conclusion
Frances C. Lawyer's contributions to the field of recombinant DNA technology are profound and impactful. His inventions not only facilitate scientific discoveries but also empower biotechnological progress. With a string of patents to his name and collaborations that foster innovation, Frances stands as a pivotal figure in the advancement of molecular biology.