Ames, IA, United States of America

Firoz Jaipuri

USPTO Granted Patents = 20 


 

Average Co-Inventor Count = 6.1

ph-index = 4

Forward Citations = 51(Granted Patents)


Company Filing History:


Years Active: 2011-2023

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20 patents (USPTO):Explore Patents

Title: Firoz Jaipuri: Innovator in Immunotherapy

Introduction

Firoz Jaipuri, based in Ames, Iowa, is a prolific inventor with a remarkable portfolio of 20 patents. His work primarily focuses on innovative solutions in the field of immunomodulation, particularly pertaining to the modulation of tryptophan metabolism. His recent patents reflect critical advancements in pharmaceutical compositions that aim to enhance cancer treatment efficacy and address immunosuppression.

Latest Patents

Firoz's latest patents include his work on TDO2 and IDO1 inhibitors. These inhibitors provide significant therapeutic benefits by modulating the activity of tryptophan 2,3-dioxygenase and indoleamine 2,3-dioxygenase 1. They are vital in treating immunosuppression and medical conditions that benefit from inhibiting tryptophan degradation. Additionally, these formulations enhance the efficacy of anti-cancer treatments when administered alongside anti-cancer agents, particularly in managing tumor-specific immunosuppression associated with cancer. Another notable patent involves salts and prodrugs of 1-methyl-d-tryptophan, specifically indoximod prodrug and salt compounds, which offer improved plasma concentration and exposure compared to direct administration of indoximod. This development is particularly promising for patients experiencing immunosuppression mediated by the indoleamine-2,3-dioxygenase pathway, including those suffering from cancer or chronic infectious diseases.

Career Highlights

Throughout his career, Firoz Jaipuri has made significant contributions while working at notable companies. His experience includes tenures at NewLink Genetics Corporation and Genentech, Inc., where he has collaborated on groundbreaking projects in the biotechnology sector.

Collaborations

Firoz has collaborated with several esteemed colleagues throughout his career, including Mario Mautino and Sanjeev Kumar. These partnerships have fostered a rich exchange of ideas and led to innovative outcomes in the field of immunotherapy.

Conclusion

Firoz Jaipuri's contributions to the field of medicine, particularly through his patents focused on immunotherapy and cancer treatment, have established him as an influential figure in the scientific community. His continued dedication to innovation and collaboration promises further advancements that can significantly impact patient care and therapeutic strategies.

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