Esta Slayton

Title: Esta Slayton: Innovator in RNA Research and Diagnostics

Introduction

Esta Slayton is a prominent inventor based in Epping, NH (US), known for her significant contributions to the field of molecular biology. With a total of four patents to her name, she has made remarkable advancements in RNA research and diagnostic methods. Her work focuses on developing innovative solutions that enhance the stability and detection of nucleic acids in biological samples.

Latest Patents

One of Esta Slayton's latest patents involves RNase inhibitors. This invention provides compositions, methods, and kits that include an inhibitory oligonucleotide RNase inhibitor capable of inhibiting various types of RNase that coexist with biological samples or are introduced in laboratory settings. This innovation protects RNA in samples from degradation, allowing for more reliable results in research and diagnostics. Additionally, her work identifies single oligonucleotides with inhibitory activity for multiple RNases, which can be combined in mixtures for enhanced efficacy. The RNase oligonucleotide inhibitor can be immobilized on beads or other surfaces and stored in either lyophilized form or in solution.

Another significant patent is a rapid diagnostic test for Loop-Mediated Isothermal Amplification (LAMP). This invention describes specific and sensitive methods for detecting target nucleic acids directly from biological samples. The compositions and methods are designed to be user-friendly, involving minimal steps while providing rapid and consistent results. This technology is applicable in both point-of-care settings and high-throughput situations. The methods utilize labelled probes and can detect target DNA from various sources, including environmental samples and individual specimens, with sensitivity to specific variants, including those of SARS-CoV-2.

Career Highlights

Esta Slayton is currently employed at New England Biolabs, Inc., where she continues to innovate in the field of molecular biology. Her work has been instrumental in advancing techniques that improve the reliability and efficiency of nucleic acid detection.

Collaborations

Esta collaborates with notable colleagues, including Nathan Tanner and Yinhua Zhang, contributing to a dynamic research environment that fosters innovation and discovery.

Conclusion

Esta Slayton's contributions to RNA research and diagnostics exemplify the impact of innovative thinking in the scientific community. Her patents reflect a commitment to enhancing the reliability of biological research and diagnostics, making her a key figure in her field.