Company Filing History:
Years Active: 2010-2019
Title: Dusan Turk: Innovator in Protein Crystallography
Introduction
Dusan Turk is a prominent inventor based in Ljubljana, Slovenia. He has made significant contributions to the field of protein crystallography, with a focus on understanding the structures of various proteins and their applications in drug design. His innovative work has led to the development of two notable patents.
Latest Patents
Dusan Turk's latest patents include the following:
1. **Crystal structure of Autolysin E, method of producing the crystal and its use in screening methods** - This invention concerns the determination and evaluation of the crystal structure of autolysin E (AtlE) or a crystallizable fragment of AtlE. It includes a method for producing a crystal of AtlE and the respective crystallization kit. The invention is useful in screening inhibitors of the N-acetylglucosaminidase activity of AtlE, providing atomic spatial relationship data and identifying binding compounds of AtlE through in silico screening.
2. **Dipeptidyl peptidase I crystal structure and its uses** - This patent relates to structural studies of dipeptidyl peptidase I (DPPI) proteins, including modified DPPI proteins and DPPI co-complexes. It encompasses a crystal of DPPI and structural information obtained by X-ray crystallography from rat and human DPPI. The invention also includes methods for using structural coordinates of DPPI, its mutants, and co-complexes to design compounds that bind to the active site or accessory binding sites of DPPI, as well as to create improved inhibitors of DPPI or its homologues.
Career Highlights
Dusan Turk has worked with esteemed organizations such as the J. Stefan Institute and Prozymex A/S. His experience in these institutions has allowed him to advance his research and contribute to the scientific community significantly.
Collaborations
Throughout his career, Dusan Turk has collaborated with notable colleagues, including Marko Mihelic and Miha Renko. These partnerships have fostered innovation and have been instrumental in his research endeavors.
Conclusion
Dusan Turk is a distinguished inventor whose work in protein crystallography has led to valuable patents that enhance our understanding of protein structures and their applications in drug development. His contributions continue to impact the field positively.