The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 01, 2019
Filed:
Apr. 27, 2015
Applicant:
J. Stefan Institute, Ljubljana, SI;
Inventors:
Assignee:
J. Stefan Institute, Ljubljana, SI;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/24 (2006.01); G16B 15/00 (2019.01); G01N 33/573 (2006.01); C12N 9/36 (2006.01);
U.S. Cl.
CPC ...
C12N 9/2402 (2013.01); C12N 9/2462 (2013.01); C12Y 302/0105 (2013.01); G01N 33/573 (2013.01); G16B 15/00 (2019.02); C07K 2299/00 (2013.01); G01N 2333/31 (2013.01); G01N 2333/924 (2013.01);
Abstract
The invention concerns the determination and evaluation of the crystal structure of autolysin E (AtlE) of(), or a crystallizable fragment of AtlE, a method for producing a crystal of AtlE and the respective crystallization kit, and its use in a method for screening an inhibitor of the N-acetylglucosaminidase activity of AtlE, for obtaining atomic spatial relationship data, and for identifying a binding compound of AtlE, e.g. by in silico screening.