Location History:
- Gainesville, FL (US) (2017 - 2019)
- Tempe, AZ (US) (2021 - 2023)
Company Filing History:
Years Active: 2017-2025
Title: Douglas Grant McFadden: Innovator in Viral Research
Introduction
Douglas Grant McFadden is a notable inventor based in Tempe, AZ (US), recognized for his contributions to viral research. He holds a total of 7 patents, showcasing his innovative approaches in the field of virology.
Latest Patents
Among his latest patents, McFadden has developed methods for improved poxvirus yields. This method involves producing poxviruses at an increased growth rate and/or progeny virus titer in cells. The process includes contacting a host cell with an effective amount of a nucleocytoplasmic transport inhibitor, allowing the poxvirus of interest to adsorb to the surface of the host cell, and culturing the host cell to produce progeny poxvirus. Additionally, he has created an oncolytic virus platform to treat cancers using myxoma virus. This platform includes recombinant myxoma viruses and nucleic acid constructs that can be engineered to express transgenes such as tumor necrosis factor (TNF) and interleukin-12 (IL-12).
Career Highlights
McFadden has worked with prominent institutions, including Arizona State University and the University of Florida Research Foundation, Incorporated. His work has significantly advanced the understanding and treatment of viral infections and cancers.
Collaborations
He has collaborated with notable colleagues such as Mohammed Masmudur Rahman and Nancy Yaneth Villa, contributing to various research projects and innovations in his field.
Conclusion
Douglas Grant McFadden's innovative work in viral research and his numerous patents highlight his significant contributions to science and medicine. His ongoing research continues to pave the way for advancements in the treatment of viral diseases and cancers.