The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 28, 2026

Filed:

Sep. 01, 2020
Applicant:

Arizona Board of Regents on Behalf of Arizona State University, Scottsdale, AZ (US);

Inventors:

Douglas Grant Mcfadden, Tempe, AZ (US);

Mohammed Masmudur Rahman, Chandler, AZ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/768 (2015.01); A61K 31/366 (2006.01); A61K 31/497 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 35/768 (2013.01); A61K 31/366 (2013.01); A61K 31/497 (2013.01); A61P 35/00 (2018.01);
Abstract

Disclosed herein are methods and compositions of treating cancer, comprising administrating to a subject with cancer a therapeutically effective amount of an oncolytic virus and a nucleocytoplasmic transport inhibitor. Further described herein are methods of converting a nonpermissive cancer cell to a permissive cancer cell and methods of killing a cancer cell by contacting the cancer cell with a therapeutically effective amount of an oncolytic vims and a nucleocytoplasmic transport inhibitor.


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