Location History:
- Midland, MI (US) (1989 - 1990)
- Cincinnati, OH (US) (1994 - 2001)
Company Filing History:
Years Active: 1989-2001
Title: **Innovative Contributions of Donald A. Kaplan**
Introduction
Donald A. Kaplan, an esteemed inventor based in Cincinnati, OH, has made significant contributions to the fields of chemistry and biomedical technology. With a portfolio of 10 patents, Kaplan’s innovations have played a crucial role in developing advanced materials and therapeutic solutions.
Latest Patents
Among his latest patents is the invention of **Dense Star Polymer Conjugates as Dyes**. This innovation features starburst conjugates composed of at least one dendrimer associated with agricultural, pharmaceutical, or other materials. The unique properties of the dendrimer offer advantageous characteristics for the conjugates.
Another notable patent is the **Family of High Affinity, Modified Antibodies for Cancer Treatment**. This invention revolves around chimeric antibodies that exhibit high affinities to a particular tumor-associated sialylated glycoprotein antigen (TAG-72) of human origin. The antibodies are designed with high-affinity animal V and V sequences, combined with human C regions, thereby minimizing side effects when administered to patients. The patent also discloses nucleotide and amino acid sequences pertinent to these chimeric antibodies, along with in vivo treatment methods and diagnostic assays.
Career Highlights
Donald A. Kaplan has held significant positions in prominent organizations such as The Dow Chemical Company and Cetus Corporation. His work in these companies contributed to advancing research and development in chemical engineering and biotechnology.
Collaborations
Throughout his career, Kaplan has collaborated with noteworthy colleagues, including Donald A. Tomalia and Larry R. Wilson. These collaborations have likely fostered an environment of innovation, paving the way for groundbreaking developments in their respective fields.
Conclusion
Donald A. Kaplan's contributions to innovations, particularly in polymer chemistry and cancer therapeutics, are commendable. His 10 patents reflect a dedication to advancing science and technology for the betterment of society. With a career marked by significant collaborations and impactful work, Kaplan's legacy as an inventor continues to inspire future generations.