Location History:
- Delmar, CA (US) (2003 - 2022)
- La Jolla, CA (US) (2020 - 2023)
Company Filing History:
11 out of 271 
5 out of 15,502 
3 out of 525 
Years Active: 2003-2025
Title: Inventor Spotlight: Don W. Cleveland
Introduction
Don W. Cleveland is a distinguished inventor based in Del Mar, California, recognized for his significant contributions to medical science through innovation. With a remarkable portfolio of 16 patents, his work primarily focuses on addressing the challenges posed by neurodegenerative diseases. Cleveland's inventions aim to improve the lives of individuals affected by debilitating conditions such as Huntington's disease and amyotrophic lateral sclerosis (ALS).
Latest Patents
Two of Don W. Cleveland's latest patents exemplify his innovative approach to combating neurodegenerative disorders. The first, titled "Modulation of Huntingtin Expression," presents methods, compounds, and compositions that facilitate the reduction of huntingtin mRNA and protein expression in animals. This groundbreaking approach is designed to treat, prevent, delay, or ameliorate Huntington's disease and its associated symptoms.
The second patent, "Compounds and Methods for Increasing STMN2 Expression," outlines novel compounds and pharmaceutical compositions aimed at enhancing the amount or activity of STMN2 RNA and protein within cells or animals. By addressing symptoms such as ataxia, neuropathy, synaptic dysfunction, cognitive deficits, and reduced longevity, this innovation holds promise for treating various neurodegenerative diseases, including frontotemporal dementia, Alzheimer's disease, and dementia with Lewy bodies.
Career Highlights
Throughout his career, Don W. Cleveland has been affiliated with leading organizations such as Ionis Pharmaceuticals, Inc. and the University of California. His endeavors in these institutions have allowed him to translate groundbreaking scientific research into practical medical solutions, showcasing his commitment to improving health outcomes.
Collaborations
Cleveland's innovative journey has been enriched by collaborations with esteemed colleagues, including C. Frank Bennett and Susan M. Freier. These partnerships have fostered a dynamic exchange of ideas and expertise, further propelling advancements in the field of neurodegenerative research.
Conclusion
Don W. Cleveland stands as a testament to the power of innovation in addressing critical health challenges. His patents demonstrate not only technical expertise but also a profound dedication to enhancing the quality of life for individuals suffering from neurodegenerative diseases. As he continues to pioneer new solutions, his work will undoubtedly leave a lasting impact in the realm of medical science and beyond.