This inventor holds 2 USPTO granted patents and 2 published patent applications. Top assignee: University of South Carolina. Active years: 2020-2021.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Elgin, SC (US) (2020)
- Columbia, SC (US) (2021)
Company Filing History:
Years Active: 2020-2021
Title: Innovations by Dominic M Casali
Introduction
Dominic M Casali is an accomplished inventor based in Columbia, SC. He has made significant contributions to the field of tissue engineering and decellularization methods. With a total of 2 patents, his work focuses on innovative techniques that enhance the quality and safety of natural polymer scaffolds.
Latest Patents
Dominic's latest patents include methods for the presaturation of supercritical carbon dioxide (CO2) with water for decellularization of matrices. This method involves exposing tissue to a water-saturated, supercritical CO2, which can be maintained at a treatment temperature of about 35°C to about 40°C. The process ensures that the water-saturated, supercritical CO2 is completely saturated with water at the treatment temperature, allowing for effective decellularization.
Another notable patent addresses the supercritical carbon dioxide extraction of residual glutaraldehyde from crosslinked collagen. This system and method provide a cleaning solution that comprises carbon dioxide and one or more polar solvents. The environmental chamber is maintained at a temperature greater than 31.1°C, and the carbon dioxide is kept at a pressure greater than 7.38 megapascals to form supercritical carbon dioxide. This innovative approach results in a crosslinked natural polymer scaffold with a glutaraldehyde content of less than about 3 parts per million.
Career Highlights
Dominic M Casali is affiliated with the University of South Carolina, where he continues to advance research in tissue engineering. His work has garnered attention for its potential applications in medical and biological fields.
Collaborations
Dominic collaborates with Michael Matthews, contributing to the development of innovative solutions in their research endeavors.
Conclusion
Dominic M Casali's contributions to the field of tissue engineering through his patents demonstrate his commitment to advancing medical technology. His innovative methods for decellularization and scaffold cleaning are paving the way for safer and more effective applications in the medical field.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile