Location History:
- Harderwijk, NL (2001)
- Hardewijk, NL (2003 - 2005)
Company Filing History:
1 out of 1 
1 out of 4 
1 out of 12,158 
Years Active: 2001-2005
Title: Dirk Franciscus Marinus Van De Wiel: Innovator in Protein Expression Technologies
Introduction
Dirk Franciscus Marinus Van De Wiel is a notable inventor based in Hardewijk, Netherlands. He has made significant contributions to the field of biotechnology, particularly in the area of protein expression systems. With a total of 3 patents to his name, Van De Wiel's work has advanced the methods used to produce recombinant proteins.
Latest Patents
Van De Wiel's latest patents include innovative methods for increasing protein expression in baculovirus vector systems. One of his notable inventions is the E2 subunit vaccine comprising recombinant pestivirus E2 protein. This invention outlines a method to enhance protein expression in insect cell cultures, which involves selecting a recombinant baculovirus, growing insect cells in a specific growth medium, and infecting the cells with the baculovirus at a defined cell density. The invention also details the production of recombinant follicle stimulating hormone and its components, achieving significant concentrations in the growth medium.
Career Highlights
Throughout his career, Van De Wiel has worked with various organizations, including the Stichting Institut Voor Dierhouderij En Diergezondheid. His expertise in biotechnology has positioned him as a key figure in the development of advanced protein expression techniques.
Collaborations
Van De Wiel has collaborated with notable professionals in his field, including Robertus Jacobus Maria Moormann and Dietmar Kretzdorn. These collaborations have further enriched his research and innovations.
Conclusion
Dirk Franciscus Marinus Van De Wiel's contributions to protein expression technologies have had a lasting impact on biotechnology. His innovative patents and collaborations highlight his role as a leading inventor in this important field.