Location History:
- Collonge, CH (2007 - 2015)
- Vufflens-le-Chateau, CH (2013 - 2019)
Company Filing History:
12 out of 297 
3 out of 3 
2 out of 1,743 
Years Active: 2007-2019
Title: The Innovations of Didier Trono
Introduction
Didier Trono is a prominent inventor based in Collonge, Switzerland. He has made significant contributions to the field of gene therapy, particularly through his work on lentiviral vectors. With a total of 15 patents to his name, Trono's innovations have the potential to revolutionize treatments for various hematological disorders.
Latest Patents
Trono's latest patents focus on methods and compositions relating to improved lentiviral vectors and their applications. These inventions provide HIV-derived lentivectors that are safe, highly efficient, and potent for expressing transgenes in human gene therapy. They are particularly effective in human hematopoietic progenitor cells and other blood cell derivatives. The lentiviral vectors feature a self-inactivating configuration for enhanced biosafety and utilize promoters such as the EF1α promoter. Additional transcription enhancing elements, like the woodchuck hepatitis virus post-transcriptional regulatory element, are also incorporated. These vectors serve as valuable tools for genetic treatments of inherited and acquired lympho-hematological disorders, gene therapies for cancers, especially hematological cancers, and for studying hematopoiesis through lentivector-mediated modification of human hematopoietic stem cells.
Career Highlights
Throughout his career, Didier Trono has worked with notable organizations, including the Research Development Foundation and the Clayton Foundation for Research. His work has significantly advanced the understanding and application of gene therapy techniques.
Collaborations
Trono has collaborated with esteemed colleagues such as Patrick Salmon and Romain N. Zufferey, contributing to the development of innovative solutions in the field of gene therapy.
Conclusion
Didier Trono's contributions to the field of gene therapy through his innovative lentiviral vectors highlight his role as a leading inventor in this critical area of research. His work continues to pave the way for advancements in genetic treatments and therapies.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.