Dennis Shull

Title: Revolutionary Innovations by Dennis Shull: Pioneering Controlled-Release Urethanes

Introduction

Dennis Shull is an accomplished inventor based in Phoenixville, Pennsylvania, recognized for his significant contributions in the field of materials science and biomedical applications. With a total of four patents to his name, he has made strides in developing innovative implantable products that leverage advanced therapeutic technologies.

Latest Patents

One of Dennis Shull's latest patents is centered around "Tunable, controlled-release, urethane-containing elastomers and processes of forming the same." This groundbreaking process involves creating an implantable product composed of poly(glycerol sebacate) urethane (PGSU) that is loaded with an active pharmaceutical ingredient (API). The method includes the homogenous mixing of a flowable poly(glycerol sebacate) (PGS) resin with the API and a catalyst, ultimately forming a resin blend. Following this, the resin blend is combined with isocyanate to generate a reaction mixture. This mixture is then injected to create the PGSU loaded with the API. Notably, in some iterations of this invention, the implantable product contains at least 40% w/w of the API. The product is designed to release the API through surface degradation of the PGSU at a finely tuned release rate for a minimum of three months under physiological conditions. Moreover, the formation of PGSU is achieved by reacting PGS with isocyanate at a specific stoichiometric ratio.

Career Highlights

Dennis Shull has demonstrated his expertise while working with notable companies such as The Secant Group, LLC and CDI Energy Products, Inc. His work has primarily focused on developing innovative solutions that address challenging problems in medical and energy applications, showcasing his versatility and depth of knowledge in various fields.

Collaborations

Throughout his career, Dennis has collaborated with talented professionals including Peter D. Gabriele and Stephanie M. Reed. Their collective expertise has fostered advanced research and development projects, further enhancing the impact of Dennis's inventions in the industry.

Conclusion

Dennis Shull's dedication to innovation is reflected in his impressive portfolio of patents that push the boundaries of technology in controlled-release therapeutics. His contributions not only enhance existing medical applications but also pave the way for future advancements in the biomedical field. As he continues to innovate and collaborate with other experts, the potential for his inventions to make a significant impact remains promising.