This inventor holds 30 USPTO granted patents and 21 published patent applications, plus 1 CIPO patent and 4 EPO patents, primarily in Monoclonal Antibodies. Top assignees: Agenus Inc., Ludwig Institute for Cancer Research Limited, Memorial Sloan Kettering Cancer Center. Active years: 1987-2025.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Location History:
- Decatur, IL (US) (1987)
- Jamaica Plain, MA (US) (2010 - 2022)
- Boston, MA (US) (2020 - 2024)
Company Filing History:
17 out of 53 
10 out of 530 
10 out of 621 
Years Active: 1987-2025
Areas of Expertise:
Title: Dennis John Underwood: Innovator in Anti-TIM-3 Antibodies
Introduction: Dennis John Underwood is a notable inventor based in Jamaica Plain, MA, recognized for his significant contributions to the field of biotechnology. With a remarkable portfolio of 28 patents, Underwood has made strides in the development of innovative therapeutic solutions, particularly focusing on anti-TIM-3 antibodies.
Latest Patents: Among his latest inventions, Underwood developed patents focusing on "Anti-TIM-3 antibodies and methods of use thereof." These patents include antibodies that specifically bind to TIM-3 and antagonize its function. Furthermore, the disclosure encompasses pharmaceutical compositions that consist of these antibodies, nucleic acids encoding them, expression vectors, host cells for producing the antibodies, and methods for treating subjects through their application. The dual emphasis on the therapeutic use of these antibodies marks a significant advancement in the treatment of diseases impacted by TIM-3 mechanisms.
Career Highlights: Dennis John Underwood has been associated with prominent organizations in the medical research sphere, including Agenus Inc. and Memorial Sloan Kettering Cancer Center. His work has been integral in advancing healthcare solutions through innovative research and development. Underwood's dedication and expertise have enabled breakthroughs that hold promise for enhancing patient outcomes.
Collaborations: Throughout his career, Underwood has worked with esteemed colleagues, including Nicholas Stuart Wilson and Gerd J Ritter. These collaborations reflect a collective effort in the pursuit of scientific advancements, showcasing the power of teamwork in driving innovation within the healthcare and biotechnology sectors.
Conclusion: Dennis John Underwood exemplifies an influential inventor whose work significantly impacts the fields of biotechnology and medicine. His dedication to developing anti-TIM-3 antibodies demonstrates not only his innovative spirit but also his commitment to improving therapeutic options for patients. As research and development continue to evolve, Underwood's contributions will likely remain instrumental in shaping future healthcare solutions.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile