Demin Zhou

Title: Demin Zhou: Innovator in Viral Research

Introduction

Demin Zhou is a prominent inventor based in Beijing, China. He has made significant contributions to the field of viral research, holding a total of 3 patents. His work focuses on innovative methods for manipulating viruses for various applications, including vaccine development.

Latest Patents

One of his latest patents is titled "Mutant virus, preparation method therefor and application thereof." This invention relates to a mutated virus, which can be an influenza virus of human or other animal origin. The method for preparing the mutated virus involves introducing UAG codons into positions upstream of the stop codons of one or more genes of a viral genome using reverse genetic techniques. The mutated virus has potential uses as a live attenuated vaccine and in the replication of controllable and safe virus models.

Another significant patent is "Adeno-associated virus with site-directed mutagenesis and site-directed modification and preparation method and application thereof." This invention pertains to an adeno-associated virus that incorporates site-directed mutagenesis and site-specific modification. The preparation method utilizes genetic code expansion techniques to include non-natural amino acids into the adeno-associated virus capsid protein VP1. This innovative approach allows the virus to couple with functional molecules and carry genes effectively, making it a valuable tool in genetic therapy and related research.

Career Highlights

Demin Zhou has worked at prestigious institutions, including Peking University and the University of Macao. His research has significantly advanced the understanding of viral mechanisms and their applications in medicine.

Collaborations

He has collaborated with notable colleagues such as Sulong Xiao and Lihe Zhang, contributing to the advancement of viral research through teamwork and shared expertise.

Conclusion

Demin Zhou's innovative work in viral research and his patented inventions highlight his role as a leading inventor in the field. His contributions have the potential to impact vaccine development and genetic therapies significantly.