Debashish Datta

Title: Innovations and Contributions of Debashish Datta

Introduction

Debashish Datta is a prominent inventor based in Hyderabad, Telangana, India. He has made significant contributions to the field of pharmaceuticals, particularly in the development of novel processes for drug synthesis. With a total of seven patents to his name, his work has had a considerable impact on the industry.

Latest Patents

One of his latest patents is an enzymatic process for the preparation of (S)-5-(4-fluoro-phenyl)-5-hydroxy-1-morpholin-4-yl-pentan-1-one, which serves as an intermediate for the drug ezetimibe. This invention outlines a method that involves the reduction of 1-(4-Fluoro-phenyl)-5-morpholin-4-yl-pentane-1,5-dione using a suitable enzyme. Additionally, it describes the steps for preparing ezetimibe, including protecting the compound, hydrolyzing, condensing with a chiral auxiliary, and other critical reactions. Another notable patent involves the polymorphic forms of perindopril (L)-arginine, which includes a novel and stable polymorphic form designated as Form γ. This invention emphasizes the greater stability of this form to heat and humidity, along with an efficient process for its large-scale preparation.

Career Highlights

Debashish Datta has worked with Mylan Laboratories Limited, where he contributed to various pharmaceutical innovations. His expertise in enzymatic processes and polymorphic forms has positioned him as a valuable asset in the field of drug development.

Collaborations

Throughout his career, Datta has collaborated with notable professionals, including Siva Rama Prasad Vellanki and Arabinda Sahu. These collaborations have further enhanced his research and development efforts.

Conclusion

Debashish Datta's contributions to the pharmaceutical industry through his innovative patents and collaborations highlight his role as a significant inventor. His work continues to influence the development of important medications, showcasing the importance of innovation in healthcare.