Company Filing History:
Years Active: 1999-2006
Title: The Innovative Contributions of Dean James Welsch
Introduction
Dean James Welsch, located in St. Peters, Missouri, is an accomplished inventor with a significant impact in the fields of biochemistry and molecular biology. With a total of two patents to his name, Welsch's work focuses on critical advancements in biomedical research, particularly in enzyme activity and the potential treatment of diseases.
Latest Patents
Welsch's latest patents showcase innovative methods and biotechnology applications. His first patent involves a peptide biomarker and method of identification, which is essential for identifying and quantifying peptides resulting from the enzyme cleavage of collagen type II. This method employs mass spectrometric analysis to detect specific peptide fragments, primarily those indicative of pathologies such as osteoarthritis and rheumatoid arthritis. The identification and quantification of these peptides facilitate the assessment of proteolytic enzyme activity in various medical conditions and the effectiveness of enzyme blocking agents.
The second patent features nucleic acids and expression vectors encoding human leukotriene C4. This patent presents DNAs that encode human LTC4 synthase, along with expression vectors comprising such DNAs. These innovations enable assay methods for detecting LTC4 synthase inhibitors while including nucleic acid probes for identifying cDNAs and genomic DNAs encoding LTC4 synthase. Moreover, it provides advanced therapeutic approaches using antisense oligonucleotides and analogs to inhibit the production of LTC4 synthase within viable cells.
Career Highlights
Throughout his career, Dean James Welsch has contributed significantly to the scientific community. He has worked with reputable companies such as Pharmacia Corporation and G.D. Searle & Company, where he honed his expertise in biotechnology and pharmaceutical innovation. These experiences provided him with a robust foundation for developing groundbreaking intellectual properties in his field of interest.
Collaborations
Welsch has collaborated with esteemed colleagues, including Kevin L. Duffin and Olga V. Nemirovskiy. Their teamwork has likely contributed to the evolution of their respective projects, leveraging collective knowledge to propel scientific advancements.
Conclusion
Dean James Welsch stands out as an influential inventor in the realms of biomedical technology and molecular research. His contributions, showcased through his patents, highlight the importance of innovation in addressing medical challenges. As research continues to evolve, Welsch's work will undoubtedly play a crucial role in advancing therapeutic strategies and enhancing patient care in the future.