The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 14, 1999
Filed:
Jun. 03, 1994
Applicant:
Inventors:
David Paul Creely, O'Fallon, MO (US);
Scott David Hauser, St. Louis, MO (US);
Dean James Welsch, St. Peters, MO (US);
Gwen Grabowski Krivi, Frontenac, MO (US);
Assignee:
G. D. Searle & Company, Skokie, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N / ; C12N / ;
U.S. Cl.
CPC ...
435193 ; 435325 ; 4353201 ; 4352542 ; 4352523 ; 536 232 ; 536 2431 ; 536 2433 ;
Abstract
DNAs which encode human LTC.sub.4 synthase and expression vectors comprising such DNAs are provided. DNAs encoding human LTC.sub.4 synthase may be used in assay methods of the invention for detecting LTC.sub.4 synthase inhibitors. Nucleic acid probes capable of identifying cDNAs and/or genomic DNAs encoding LTC4 synthase, as well as LTC.sub.4 antisense oligonucleotides and analogs which may be administered to viable cells to inhibit production of LTC.sub.4 synthase are also provided.